Description

4,3-Premercapturic Acid is a specialized organic sulfur compound, recognized as a key biomarker and intermediate in biochemical research. Its significance lies in its role for studying metabolic pathways and exposure to specific xenobiotics, providing critical insights for toxicological and pharmaceutical development. This high-purity material is essential for research laboratories, analytical reference standard producers, and companies developing diagnostic assays within the life sciences sector.

Application

• Biomarker Research: Used as a reference standard in studies investigating human metabolism and exposure to industrial or environmental chemicals.
• Analytical Chemistry: Serves as a critical calibration standard for advanced techniques like LC-MS/MS and HPLC in forensic and clinical toxicology.
• Diagnostic Development: Employed in the research and production of diagnostic kits and assays designed to detect specific mercapturic acid conjugates.
• Toxicology Studies: A vital tool for understanding detoxification pathways, specifically the glutathione conjugation pathway, in both in vitro and in vivo models.
• Pharmaceutical R&D: Utilized as a building block or reference compound in the development of novel therapeutics targeting sulfur metabolism.
• Academic Research: Supports fundamental chemical and biochemical research in universities and government institutions.

Basic Information

Product Name	4,3-Premercapturic Acid
CAS No.	21125-60-0
Molecular Formula	C9H15NO5S
Molecular Weight	249.29 g/mol
Synonyms	N-Acetyl-S-(3,4-dihydroxybutyl)-L-cysteine; DHBMA; 1-Mercapturic Acid; 3,4-Dihydroxybutyl Mercapturic Acid; N-Acetyl-S-(3,4-dihydroxybutyl)cysteine; Pre-Mercapturic Acid Metabolite; L-Cysteine, N-acetyl-S-(3,4-dihydroxybutyl)-; Butane-1,2,4-triol, 1-(N-acetylcystein-S-yl)-
EINECS	Contact for details

Quality Control

Our 4,3-Premercapturic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive analytical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines for reference standard materials to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.