Description

Methyllycaconitine Citrate Mla:Synthetic CAS NO 21019-30-7 is a high-purity synthetic alkaloid derivative, specifically the citrate salt of methyllycaconitine (MLA). This compound is a potent and selective competitive antagonist of α7 nicotinic acetylcholine receptors (nAChRs), making it a critical research tool in neuroscience and pharmacology. It is essential for researchers and developers in the pharmaceutical and life sciences sectors who require precise, reliable ligands for receptor characterization, neurological pathway studies, and the development of novel therapeutic agents targeting cholinergic systems.

Application

• Neuroscience Research: As a selective α7 nAChR antagonist for studying receptor function, signal transduction, and neuronal communication.
• Pharmacological Studies: Used in vitro and in vivo to investigate the role of α7 nAChRs in cognitive function, neuroprotection, and inflammatory responses.
• Drug Discovery & Development: A key reference standard and tool compound for screening and validating new drug candidates targeting nicotinic acetylcholine receptors.
• Biochemical Assay Development: Employed in the development and calibration of high-throughput screening (HTS) assays and binding studies.
• Toxicology Research: Used to study the mechanisms of action of related natural alkaloids and to explore neurotoxicological pathways.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in neurochemistry and cellular physiology.

Basic Information

Product Name	Methyllycaconitine Citrate Mla:Synthetic
CAS No.	21019-30-7
Molecular Formula	C37H50N2O10 • xC6H8O7
Molecular Weight	Contact for details
Synonyms	MLA Citrate; Methyllycaconitine Citrate Salt; (1α,6α,14α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-7,8,14-triol Citrate; Lycoctonine, 14,16-didehydro-20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, citrate (1:1); α7 nAChR Antagonist (MLA); Synthetic Methyllycaconitine Citrate
EINECS	Contact for details

Quality Control

Our Methyllycaconitine Citrate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot is analyzed using advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.