Description

15(R)-Prostaglandin E1 is a stereoisomer of the bioactive lipid mediator Prostaglandin E1 (Alprostadil). This compound is of significant interest in advanced pharmaceutical research and development due to its specific biological activity profile. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutics, particularly for investigating vascular and inflammatory pathways.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of specialized prostaglandin analogs and related bioactive compounds.
• Biochemical Research: Used as a reference standard and active agent in studies of prostaglandin receptors (EP receptors) and their downstream signaling mechanisms.
• Vascular Biology Studies: Employed in preclinical research to investigate effects on vasodilation, platelet aggregation, and vascular smooth muscle cell proliferation.
• Inflammation & Immunology Research: Applied in cellular assays to study the modulation of inflammatory cytokines and immune cell function.
• Process Development: Serves as a critical material in the development and optimization of stereoselective synthetic routes within process chemistry.

Basic Information

Product Name	15(R)-Prostaglandin E1
CAS No.	20897-91-0
Molecular Formula	C₂₀H₃₄O₅
Molecular Weight	354.48 g/mol
Synonyms	15(R)-PGE1; (15R)-Prostaglandin E1; 15R-PGE1; Alprostadil Impurity/Isomer; 11α,15R-Dihydroxy-9-oxoprost-13-en-1-oic Acid; (5Z,11α,13E,15R)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid; 15-epi-Prostaglandin E1
EINECS	Contact for details

Quality Control

Our 15(R)-Prostaglandin E1 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, related substances, and other critical parameters to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.