Description

3,4-Bis(Trifluoromethyl)Pyridine is a high-value, fluorinated heterocyclic building block characterized by its two electron-withdrawing trifluoromethyl groups. This compound matters for its unique ability to impart significant lipophilicity, metabolic stability, and altered electronic properties to target molecules, making it a critical intermediate in advanced synthesis. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the CF3 groups enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in cross-coupling and other organic transformations.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials to modify solubility and dielectric properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems due to its fluorine atoms' utility in 19F NMR spectroscopy.

Basic Information

Product Name	3,4-Bis(Trifluoromethyl)Pyridine
CAS No.	20857-46-9
Molecular Formula	C7H3F6N
Molecular Weight	215.10 g/mol
Synonyms	3,4-Di(trifluoromethyl)pyridine; Pyridine, 3,4-bis(trifluoromethyl)-; 3,4-Bis(trifluoromethyl)pyridine; 20857-46-9; 3,4-Bistrifluoromethylpyridine; 3,4-Bis(trifluoromethyl)pyridin; 3,4-Ditrifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 3,4-Bis(Trifluoromethyl)Pyridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.