Description

13,14-Dihydro-15-Keto-Tetranor Prostaglandin E2 is a key metabolite and synthetic intermediate in the study of prostaglandin pathways. This compound is of significant value for pharmaceutical research and development, particularly in the investigation of inflammation, renal function, and metabolic processes. It is primarily sought by research institutions, pharmaceutical companies, and advanced chemical manufacturers engaged in the synthesis of bioactive molecules and analytical reference standards.

Application

• Pharmaceutical Research & Development: Critical intermediate in the synthesis of novel prostaglandin analogs and metabolites for therapeutic exploration.
• Biochemical Research: Used as a reference standard and analytical tool in metabolic pathway studies, enzyme assays, and receptor binding studies.
• Diagnostic Reagent Manufacturing: Serves as a key component in the development of diagnostic kits and assays for measuring prostaglandin metabolites in biological samples.
• Academic & Institutional Research: Employed in universities and research labs for studying the physiological and pathophysiological roles of eicosanoids.
• Process Development: Used in scaling up synthetic routes for prostaglandin-related active pharmaceutical ingredients (APIs).
• Quality Control & Analytical Standards: Provides a high-purity standard for HPLC, LC-MS, and other analytical methods to ensure product quality and consistency.

Basic Information

Product Name	13,14-Dihydro-15-Keto-Tetranor Prostaglandin E2
CAS No.	20675-85-8
Molecular Formula	C16H26O5
Molecular Weight	298.37 g/mol
Synonyms	15-Keto-13,14-dihydro-PGE2 tetranor; DHK-PGE2 tetranor; Tetranor PGE2 metabolite; 13,14-Dihydro-15-oxo-tetranor-prostaglandin E2; 7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid; 15-Keto-13,14-dihydro-tetranor-PGE2; PGEM-II (Prostaglandin E Metabolite II); 11-Deoxy-13,14-dihydro-15-keto-11,16-cyclo-tetranor PGE2 (related structure).
EINECS	Contact for details

Quality Control

Our 13,14-Dihydro-15-Keto-Tetranor Prostaglandin E2 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical work.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.