Description

1-Butyl-4-Fluoro-Benzene is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a fluorine atom and a butyl chain on a benzene ring, makes it a critical intermediate for creating more complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Polymer & Resin Modifier: Employed to introduce fluorine and aromatic groups into polymer chains, enhancing chemical resistance, thermal stability, and surface properties of specialty plastics and coatings.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions (e.g., Suzuki, Heck) and as a starting material for further functionalization to create complex organic molecules for research and development.

Basic Information

Item	Detail
Product Name	1-Butyl-4-Fluoro-Benzene
CAS No.	20651-65-4
Molecular Formula	C₁₀H₁₃F
Molecular Weight	152.21 g/mol
Synonyms	4-Fluorobutylbenzene; p-Butylfluorobenzene; 4-Butylfluorobenzene; 1-Fluoro-4-butylbenzene; Butylfluorobenzene; 4-Fluoro-1-butylbenzene; (4-Fluorophenyl)butane; p-Fluorobutylbenzene
EINECS	Contact for details

Quality Control

Our 1-Butyl-4-Fluoro-Benzene is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~0.95 g/mL
Refractive Index (n20D)	~1.48

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.