Description

13,14-Dihydro Prostaglandin F1Alpha is a stable dihydro analog of the primary prostaglandin PGF1α. This compound is valued as a key biochemical tool and synthetic intermediate for research into prostaglandin metabolism, receptor activity, and signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and fine chemical manufacturers engaged in the development of bioactive lipid analogs and related therapeutic agents.

Application

• Biochemical Research: Used as a stable reference standard and probe for studying prostaglandin biology, enzyme kinetics (e.g., 15-hydroxyprostaglandin dehydrogenase), and receptor-ligand interactions.
• Pharmaceutical Intermediate: Serves as a critical synthetic building block for the preparation of more complex prostaglandin analogs and derivatives with potential therapeutic applications.
• Cell Signaling Studies: Employed in in vitro and ex vivo models to investigate the role of prostaglandins in physiological and pathological processes such as inflammation, smooth muscle contraction, and renal function.
• Analytical Standard: Provides a high-purity calibrant for quantitative analytical methods, including HPLC and LC-MS, in bioanalytical and quality control laboratories.
• Metabolite Analysis: Essential for the identification and quantification of prostaglandin metabolites in complex biological matrices during pharmacokinetic and metabolic studies.

Basic Information

Product Name	13,14-Dihydro Prostaglandin F1Alpha
CAS No.	20592-20-5
Molecular Formula	C₂₀H₃₆O₅
Molecular Weight	356.50 g/mol
Synonyms	13,14-Dihydro-PGF1α; 9α,11α,15S-Trihydroxy-13,14-dihydroprost-5-en-1-oic Acid; 13,14-Dihydroprostaglandin F1α; DH-PGF1α; (5Z)-9,11,15-Trihydroxy-13,14-dihydroprost-5-enoic Acid; PGF1α Dihydro Analog; Prostaglandin F1α Dihydro Derivative
EINECS	Contact for details

Quality Control

Our 13,14-Dihydro Prostaglandin F1Alpha is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by HPLC to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store unopened vials at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.