Description

4'-Chloro[1,1'-Biphenyl]-4-Sulfonyl Chloride is a high-purity, bifunctional organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its dual reactive sites, the sulfonyl chloride and the aryl chloride, which enable its use as a versatile building block for creating complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that require a biphenyl sulfonyl chloride core.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and liquid crystal materials.
• Dyestuff and Pigment Manufacturing: Intermediate for creating high-performance, color-fast organic dyes and pigments.
• Chemical Research & Development: A versatile reagent for constructing complex biphenyl derivatives in medicinal and process chemistry.

Basic Information

Product Name	4'-Chloro[1,1'-Biphenyl]-4-Sulfonyl Chloride
CAS No.	20443-74-7
Molecular Formula	C12H8Cl2O2S
Molecular Weight	287.16 g/mol
Synonyms	4'-Chlorobiphenyl-4-sulfonyl chloride; 4-Chloro-4'-sulfonylchlorobiphenyl; (4'-Chloro[1,1'-biphenyl]-4-yl)sulfonyl chloride; p-Chlorophenyl phenyl sulfone chloride; 1-Chloro-4-(4-chlorophenyl)sulfonyl)benzene; Biphenyl-4-sulfonyl chloride, 4'-chloro-; 4-(4-Chlorophenyl)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4'-Chloro[1,1'-Biphenyl]-4-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and specialty chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.