Description

(+-)-Prostaglandin E1 CAS NO 20348-58-7 is a synthetic analog of the naturally occurring lipid mediator, Prostaglandin E1 (PGE1), also known as Alprostadil. This compound is a critical intermediate and reference standard in pharmaceutical research and development, valued for its potent vasodilatory and antiplatelet aggregation properties. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on cardiovascular therapeutics, inflammation studies, and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced prostaglandin-based drugs and analogs.
• Biochemical Research: Used as a reference standard and active agent in studies of inflammation, pain pathways, and vascular biology.
• Drug Discovery & Development: A vital tool for high-throughput screening (HTS) and target validation in cardiovascular and inflammatory disease research.
• Cell Signaling Studies: Employed to investigate the role of prostaglandin receptors (EP receptors) in various physiological and pathological processes.
• Veterinary Medicine: Potential applications in veterinary pharmaceuticals for managing circulatory conditions.

Basic Information

Product Name	(+-)-Prostaglandin E1
CAS No.	20348-58-7
Molecular Formula	C₂₀H₃₄O₅
Molecular Weight	354.48 g/mol
Synonyms	Alprostadil; PGE1; Prostaglandin E1; 11α,15α-Dihydroxy-9-oxoprost-13-en-1-oic acid; (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; (±)-Prostaglandin E1; Prostin VR
EINECS	Contact for details

Quality Control

Our (+-)-Prostaglandin E1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. For long-term stability, the product should be kept in a freezer. Allow the sealed vial to equilibrate to room temperature before opening to avoid moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.