Description

2,6-Dimethylbenzenesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, introducing the robust and modifiable 2,6-dimethylbenzenesulfonyl group into target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to create sulfonamides, sulfonate esters, and other functional intermediates.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating sulfonamide-based drugs with antibacterial, diuretic, or anti-inflammatory properties.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the sulfonyl moiety contributes to biological activity and stability.
• Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialty polymers, including polyelectrolytes and engineering plastics.
• Dye and Pigment Manufacturing: Employed in the synthesis of sulfonated dyes and colorants to enhance solubility and fiber affinity.
• Chemical Research & Development: A fundamental tool for medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Ligand and Catalyst Preparation: Used to synthesize chiral auxiliaries and ligands for asymmetric catalysis.

Basic Information

Item	Details
Product Name	2,6-Dimethylbenzenesulfonyl Chloride
CAS No.	2905-29-5
Molecular Formula	C8H9ClO2S
Molecular Weight	204.67 g/mol
Synonyms	2,6-Dimethylbenzenesulfonyl chloride; 2,6-Xylenesulfonyl chloride; 2,6-Dimethylphenylsulfonyl chloride; o-Xylene-2-sulfonyl chloride; 2,6-DMBSC; 2,6-Dimethylbenzene-1-sulfonyl chloride; 2,6-Dimethylbenzenesulfochloride; 2,6-Xylylsulfonyl chloride
EINECS	220-828-5

Quality Control

Our 2,6-Dimethylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.