Description

2-Bromobenzenesulphonyl Chloride is a versatile and reactive organosulfur compound that serves as a key building block in advanced organic synthesis. Its primary value lies in its dual functionality, acting as both an electrophilic sulfonylation agent and a substrate for further functionalization via the bromine substituent. This chemical is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to construct complex sulfonamide and sulfonate ester derivatives. The compound's reactivity profile makes it indispensable for creating molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs with antibacterial, diuretic, or anti-carbonic anhydrase properties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the sulfonyl chloride group is incorporated to enhance biological efficacy and environmental stability.
• Material Science & Polymer Chemistry: Employed as a monomer or cross-linking agent to introduce sulfone groups into polymers, improving thermal stability and chemical resistance.
• Dye & Pigment Manufacturing: Serves as an intermediate for producing sulfonated dyes and pigments, which offer improved solubility and color fastness.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new reaction pathways, creating chemical libraries, and developing novel catalytic processes.
• Ligand & Catalyst Preparation: Utilized to synthesize specialized ligands for metal complexes and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Bromobenzenesulphonyl Chloride
CAS No.	2905-25-1
Molecular Formula	C6H4BrClO2S
Molecular Weight	255.52 g/mol
Synonyms	o-Bromobenzenesulfonyl Chloride; 2-Bromobenzene-1-sulfonyl Chloride; Benzenesulfonyl Chloride, 2-bromo-; o-Bromophenylsulfonyl Chloride; 2-Bromophenylsulfonyl Chloride; NSC 404083; BSC
EINECS	220-825-9

Quality Control

Our 2-Bromobenzenesulphonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and titration methods. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable consistency and traceability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage, consider refrigeration (2-8°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or lumps
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.