Description

2-Fluorobenzenesulfonyl Chloride is a key fluorinated aromatic sulfonyl chloride building block used extensively in organic synthesis. Its primary value lies in its reactivity as a sulfonylation agent, enabling the introduction of the 2-fluorobenzenesulfonyl moiety to create novel compounds with tailored properties. This intermediate is particularly critical for researchers and manufacturers in the pharmaceutical and agrochemical industries developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A vital precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and stability.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced functional materials.
• Chemical Research & Development: Employed in academic and industrial R&D for constructing complex molecules and exploring new synthetic pathways.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized fluorinated dyes and colorants.

Basic Information

Product Name	2-Fluorobenzenesulfonyl Chloride
CAS No.	2905-21-7
Molecular Formula	C6H4ClFO2S
Molecular Weight	194.61 g/mol
Synonyms	o-Fluorobenzenesulfonyl Chloride; 2-Fluorobenzene-1-sulfonyl Chloride; 1-Fluoro-2-(chlorosulfonyl)benzene; Benzenesulfonyl Chloride, 2-fluoro-; 2-Fluorophenylsulfonyl Chloride
EINECS	220-826-5

Quality Control

Our 2-Fluorobenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.