Description

Acetoxycycloheximide is a potent, semi-synthetic derivative of the natural compound cycloheximide, characterized by the introduction of an acetoxy group. This modification is crucial for enhancing its stability and biological activity profile, making it a valuable tool compound in life science research. It is primarily sought after by researchers in the pharmaceutical, biotechnology, and agrochemical sectors for its specific inhibitory properties. The compound is supplied under stringent quality control to ensure reliability and reproducibility in critical experimental applications.

Application

• Biochemical Research: Used as a potent and specific inhibitor of eukaryotic protein synthesis in cell biology and molecular biology studies.
• Pharmaceutical Development: Serves as a key reference standard and tool for investigating protein synthesis pathways and screening for novel antibiotics or antifungal agents.
• Antifungal Studies: Employed in research to study fungal growth inhibition mechanisms and to evaluate the efficacy of new antifungal formulations.
• Plant Physiology Research: Utilized to study protein synthesis in plant cells and to investigate plant-pathogen interactions.
• Cell Cycle Analysis: Applied in cancer research to arrest cells at specific phases for studying cell cycle regulation and apoptosis.
• Enzyme Inhibition Assays: Acts as a specific inhibitor in enzymatic studies related to translation elongation in eukaryotic systems.

Basic Information

Product Name	Acetoxycycloheximide
CAS No.	2885-39-4
Molecular Formula	C17H25NO5
Molecular Weight	323.39 g/mol
Synonyms	Naramycin B; Cycloheximide acetate; 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide 4-acetate; 4-Acetoxycycloheximide; Antibiotic 452-1; Actidione acetate; Actispray acetate; 2885-39-4
EINECS	220-765-7

Quality Control

Our Acetoxycycloheximide is manufactured and tested under a strict quality management system to ensure the highest standards of purity and consistency for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to guarantee the material's suitability as a high-grade biochemical reagent. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Solubility	Soluble in DMSO, ethanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.