Description

8-Benzyltheophylline is a xanthine derivative and a key chemical intermediate with significant pharmacological research applications. This compound is valued for its role as a precursor in the synthesis of more complex molecules, particularly those targeting adenosine receptor activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of cardiovascular, neurological, and respiratory therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel adenosine receptor antagonists and other xanthine-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and tool compound in studies investigating adenosine signaling pathways and their physiological effects.
• Cardiovascular Research: Employed in preclinical research for developing compounds with potential vasodilatory and cardioprotective properties.
• Neurological Research: Investigated for its potential role in modulating neuroprotective or neurostimulant pathways related to adenosine receptors.
• Respiratory Agent Development: Serves as a precursor in research for bronchodilator agents due to the structural relationship to theophylline.
• Chemical Synthesis: Used in organic synthesis for introducing the benzyl-theophylline moiety into more complex molecular architectures.

Basic Information

Product Name	8-Benzyltheophylline
CAS No.	2879-15-4
Molecular Formula	C₁₄H₁₄N₄O₂
Molecular Weight	270.29 g/mol
Synonyms	8-Benzyl-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 8-Benzyl-1,3-dimethylxanthine; 1,3-Dimethyl-8-benzylxanthine; Theophylline, 8-benzyl-; 8-Benzyltheophylline; 8-(Phenylmethyl)theophylline; NSC 408981
EINECS	220-732-7

Quality Control

Our 8-Benzyltheophylline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and residual solvent analysis, to ensure it meets high-purity standards suitable for research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.