Description

Cholesterol 7-Hydroperoxide is a specific oxidized derivative of cholesterol, a key intermediate in the study of lipid peroxidation and oxidative stress pathways. This compound matters significantly for researchers and developers investigating the mechanisms of atherosclerosis, aging, and other diseases linked to oxidative damage of biomolecules. It is primarily needed by pharmaceutical R&D teams, academic biochemistry laboratories, and diagnostic kit manufacturers focused on cardiovascular and metabolic disease research.

Application

• Biochemical Research: Used as a critical standard and reagent in studies of cholesterol oxidation mechanisms and the biological effects of oxysterols.
• Pharmaceutical Development: Serves as a reference compound in the development and validation of assays for screening antioxidant or anti-atherosclerotic drug candidates.
• Diagnostic Marker Studies: Employed in research to quantify and understand the role of specific cholesterol hydroperoxides as potential biomarkers for oxidative stress in clinical samples.
• Food & Cosmetic Science: Utilized in stability testing and research into the oxidation pathways of cholesterol in complex matrices like dairy products or cosmetic formulations.
• Analytical Method Development: Acts as a high-purity calibration standard for advanced analytical techniques such as LC-MS/MS and HPLC in lipidomics.

Basic Information

Product Name	Cholesterol 7-Hydroperoxide
CAS No.	2846-29-9
Molecular Formula	C₂₇H₄₆O₃
Molecular Weight	418.66 g/mol
Synonyms	7-Hydroperoxycholesterol; 5-Cholesten-3β-ol-7α-hydroperoxide; 7α-Hydroperoxycholest-5-en-3β-ol; Cholesterol 7α-Hydroperoxide; 7α-Hydroperoxy Cholesterol; 7-OOH Cholesterol; 7α-OOH Chol
EINECS	220-644-4

Quality Control

Our Cholesterol 7-Hydroperoxide is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for high-purity biochemicals, ensuring material integrity from synthesis to shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize further oxidation and degradation. Allow the container to reach room temperature in a desiccator before opening to prevent condensation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in chloroform, ethanol; sparingly soluble in hexane

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.