Description

1-Fluoro-2,3,5-Tribromobenzene is a halogenated aromatic compound of significant interest in advanced organic synthesis. This multi-halogenated benzene derivative serves as a versatile and valuable building block for the construction of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists for applications requiring selective functionalization and the introduction of specific halogen patterns.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex halogen-substituted aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the specific bromine/fluorine substitution pattern influences biological activity.
• Material Science Research: Serves as a monomer or building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, allowing for selective derivatization.
• Ligand and Catalyst Development: Utilized in the preparation of specialized phosphine or nitrogen-based ligands for asymmetric catalysis.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1-Fluoro-2,3,5-Tribromobenzene
CAS No.	2839-37-4
Molecular Formula	C6H2Br3F
Molecular Weight	332.79 g/mol
Synonyms	2,3,5-Tribromofluorobenzene; 1,2,4-Tribromo-5-fluorobenzene; Fluorotribromobenzene; Benzene, 1-fluoro-2,3,5-tribromo-; 5-Fluoro-1,2,4-tribromobenzene; F-TBB
EINECS	220-618-3

Quality Control

Our 1-Fluoro-2,3,5-Tribromobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports your regulatory needs in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.