Description

Tyrphostin A1 is a potent and selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. This compound is a valuable research tool for studying signal transduction pathways, cellular proliferation, and apoptosis. It is primarily utilized by researchers and scientists in the fields of oncology, biochemistry, and pharmacology for target validation and mechanistic studies.

Application

• Biochemical Research: Used as a selective EGFR tyrosine kinase inhibitor to study receptor-mediated signaling cascades.
• Oncology Research: Investigated for its effects on cancer cell proliferation, survival, and tumor growth in preclinical models.
• Signal Transduction Studies: A key tool for dissecting the role of EGFR in various cellular processes and disease states.
• Pharmacology & Drug Discovery: Serves as a reference compound for screening and developing novel targeted cancer therapeutics.
• Academic & Institutional Research: Employed in university and institutional labs for fundamental biological research.

Basic Information

Product Name	Tyrphostin A1
CAS No.	2826-26-8
Molecular Formula	C16H12N2O3
Molecular Weight	280.28 g/mol
Synonyms	AG 82; RG 50810; Tyrphostin AG 82; 2-[(3,4,5-Trimethoxyphenyl)methylene]malononitrile; 2-[(3,4,5-Trimethoxybenzylidene)]malononitrile; 3,4,5-Trimethoxybenzylidenemalononitrile; EGFR Inhibitor AG 82
EINECS	220-596-1

Quality Control

Our Tyrphostin A1 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.