Description

2,4-Difluoropyrimidine is a versatile fluorinated heterocyclic building block essential for modern synthetic chemistry. Its value lies in its ability to act as a key precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and advanced materials. Its specific reactivity profile makes it a critical intermediate for introducing the pyrimidine scaffold with fluorine substituents.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of antiviral, anticancer, and kinase inhibitor drugs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and electronic materials.
• Chemical Biology & Proteomics: Employed in the design of molecular probes, tags, and inhibitors for studying biological systems.
• Fluorination Chemistry: Acts as a fluorinating agent or a stable source of fluorine in complex synthetic routes.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,4-Difluoropyrimidine
CAS No.	2802-61-1
Molecular Formula	C4H2F2N2
Molecular Weight	116.07 g/mol
Synonyms	2,4-Difluoropyrimidine; Pyrimidine, 2,4-difluoro-; 2,4-Difluoro-1,3-diazine; 2,4-Difluoropyrimidine (DFP); 2,4-Difluoro-pyrimidine; 2,4-Difluor-1,3-diazin; 2,4-Difluoropyrimidine, 98+%; 2,4-Difluoropyrimidine (stabilized)
EINECS	220-549-8

Quality Control

Our 2,4-Difluoropyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to confirm identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.