Description

Gambogic Acid CAS NO 2752-65-0 is a natural xanthonoid compound derived from the resin of Garcinia hanburyi trees. This bioactive molecule is of significant interest for its potent and selective anti-cancer properties, primarily through the induction of apoptosis. It serves as a critical reference standard and active pharmaceutical ingredient (API) for researchers and developers in the pharmaceutical, biotechnology, and nutraceutical industries.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) in the development of novel anti-cancer therapeutics.
• Biochemical & Cell Biology Studies: Used as a potent inducer of apoptosis (programmed cell death) to study signaling pathways in various cancer cell lines.
• Natural Product & Medicinal Chemistry: Serves as a lead compound for structural modification and synthesis of derivatives with enhanced efficacy and reduced toxicity.
• Quality Control & Analytical Testing: Employed as a high-purity certified reference material (CRM) for HPLC, LC-MS, and other analytical methods in QC laboratories.
• Preclinical In Vivo Studies: Utilized in animal model research to investigate pharmacokinetics, bioavailability, and therapeutic efficacy of gambogic acid and its formulations.
• Nutraceutical Formulation: Incorporated as a standardized bioactive component in advanced dietary supplement research (subject to regulatory approval).

Basic Information

Item	Detail
Product Name	Gambogic Acid
CAS No.	2752-65-0
Molecular Formula	C38H44O8
Molecular Weight	628.75 g/mol
Synonyms	Gambogic Acid; β-Guttiferin; 1,3,5-Trihydroxy-6-(3,7,11-trimethyldodeca-2,6,10-trienyl)-9H-xanthen-9-one; Garcinia Acid; Morellin Dimethyl Acetal; NSC 3640; 2-Butenoic acid, 4-[(1S,5R,7R,8S)-8-hydroxy-5-(2-hydroxy-3-methyl-3-butenyl)-7-(3-methyl-2-butenyl)-1,4,4a,5,6,7,8,8a-octahydro-2,5-methano-2H-1-benzoxepin-1-yl]-, (2E)-; CI 75300
EINECS	220-403-6

Quality Control

Our Gambogic Acid is produced and tested under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere for long-term stability. This product is easily oxidized and light-sensitive; handling should minimize exposure to air and light.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Solubility	Soluble in DMSO, methanol; slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.