Description

Acetic Anhydride, [1-14C] is a carbon-14 labeled isotopologue of acetic anhydride, a vital reagent in organic synthesis. This radiolabeled compound is essential for tracing metabolic pathways and studying reaction mechanisms in pharmaceutical and biochemical research. It is primarily used by scientists in drug discovery, metabolism studies, and analytical chemistry who require precise tracking of acetyl group transfer.

Application

• Tracer Studies in Drug Metabolism and Pharmacokinetics (DMPK): Used to label and track the fate of acetyl groups in novel drug candidates within biological systems.
• Biochemical Pathway Analysis: Essential for elucidating acetylation mechanisms in enzymatic reactions and metabolic processes.
• Organic Synthesis Intermediate: Serves as a radiolabeled acetylating agent for the synthesis of 14C-labeled target molecules for research.
• Analytical Reference Standard: Employed as a critical standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and other analytical methods for quantification and method validation.
• Material Science Research: Used in the study of acetylation reactions on polymers and other materials where tracking is required.

Basic Information

Product Name	Acetic Anhydride, [1-14C]
CAS No.	2742-27-0
Molecular Formula	C4H614CO3
Molecular Weight	104.07 g/mol (for unlabeled); Contact for labeled specific activity
Synonyms	Acetic-1-14C Anhydride; [1-14C]Acetic Anhydride; Ethanoic-1-14C Anhydride; Acetyl-1-14C Oxide; (14C)Ac2O; 1-14C-Acetic Anhydride; Radiolabeled Acetic Anhydride; Carbon-14 Labeled Acetic Anhydride
EINECS	220-395-0 (for unlabeled acetic anhydride)

Quality Control

Every batch of Acetic Anhydride, [1-14C] is produced and analyzed under strict quality systems to ensure high chemical and radiochemical purity, specific activity, and stability. Quality is verified by advanced techniques including HPLC, NMR, and radiometric detection. A comprehensive Certificate of Analysis (COA) detailing purity, specific activity, solvent, and analytical methods is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. Due to its nature as a strong acid/organic solvent and highly volatile compound, ensure storage in a well-ventilated area, away from heat and incompatible materials. For long-term stability, consult the specific COA for recommended storage conditions.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (NMR/IR)	Conforms to structure
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Contact for details (mCi/mmol)
Solvent	Specified on COA
Concentration	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.