Description

2-Phenoxybenzene-1-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. This compound matters for its role as a versatile electrophilic reagent, enabling the introduction of the 2-phenoxybenzenesulfonyl moiety to create novel molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for synthesizing active ingredients and specialty intermediates.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of sulfonamide-based drug candidates, including protease inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of novel herbicides and fungicides that require specific sulfonyl functional groups for bioactivity.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the development of specialty polymers, such as sulfonated polyaryletherketones for membrane applications.
• Dye and Pigment Manufacturing: Intermediate for creating sulfonated dyes and colorants with enhanced solubility and fastness properties.
• Material Science Research: Employed in surface modification and the creation of self-assembled monolayers (SAMs) on various substrates.
• Chemical Biology Probes: Useful for labeling proteins or other biomolecules via sulfonylation reactions in biochemical research.

Basic Information

Product Name	2-Phenoxybenzene-1-Sulfonyl Chloride
CAS No.	2688-85-9
Molecular Formula	C12H9ClO3S
Molecular Weight	268.72 g/mol
Synonyms	2-Phenoxybenzenesulfonyl chloride; (2-Phenoxyphenyl)sulfonyl chloride; 2-Phenoxybenzene sulfonyl chloride; o-Phenoxybenzenesulfonyl chloride; 1-Chlorosulfonyl-2-phenoxybenzene; 2-Phenoxy-1-benzenesulfonyl chloride; Phenoxy phenyl sulfonyl chloride; PPS-Cl
EINECS	Contact for details

Quality Control

Our 2-Phenoxybenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere such as nitrogen or argon after opening. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0 - 103.0 %
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.