Description

2,5-Difluorobenzaldehyde is a versatile aromatic aldehyde building block characterized by its two strategically placed fluorine atoms on the benzene ring. This compound is highly valued for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries such as fine chemical manufacturing, pharmaceutical R&D, and advanced material science rely on this high-purity intermediate to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the difluoro substitution pattern enhances biological activity and stability.
• Liquid Crystal & OLED Material: Serves as a building block for fluorine-containing organic electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Functional Dye & Pigment Intermediate: Employed in the production of specialized dyes and pigments where fluorine atoms improve light fastness and chemical resistance.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Organic Synthesis & Research: A valuable reagent in academic and industrial research laboratories for exploring new fluorinated compounds and reaction methodologies.

Basic Information

Item	Detail
Product Name	2,5-Difluorobenzaldehyde
CAS No.	2646-90-4
Molecular Formula	C7H4F2O
Molecular Weight	142.10 g/mol
Synonyms	2,5-Difluorobenzaldehyde; Benzaldehyde, 2,5-difluoro-; 2,5-Difluorobenzenecarboxaldehyde; α,2,5-Trifluorotoluene (obsolete); 2,5-Difluorophenylmethanal; 2,5-DFB; 2,5-Difluoro benzaldehyde
EINECS	220-169-7

Quality Control

Our 2,5-Difluorobenzaldehyde is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP or research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening to maintain purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.