Description

4-Amino-5-Chloro-n-[2-(Diethylamino)Ethyl]-2-Methoxybenzamide Dihydrochloride is a high-purity, pharmacologically active benzamide derivative. This compound is a critical intermediate in the synthesis of specialized pharmaceutical agents, where its structural integrity directly influences final product efficacy and safety. It is essential for research and development chemists and manufacturers in the pharmaceutical industry, particularly those focused on developing gastrointestinal and neurological therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potent dopamine D2 receptor antagonists and gastroprokinetic agents.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step production of final drug substances requiring a specific benzamide pharmacophore.
• Biochemical Research: Serves as a reference standard and a precursor in studies investigating receptor binding and signal transduction pathways.
• Process Development & Scale-Up: Employed in optimizing synthetic routes for commercial manufacturing of target drug molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-Amino-5-Chloro-n-[2-(Diethylamino)Ethyl]-2-Methoxybenzamide Dihydrochloride
CAS No.	2576-84-3
Molecular Formula	C16H27Cl2N3O2
Molecular Weight	364.31 g/mol
Synonyms	Clebopride Dihydrochloride; 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide dihydrochloride; 4-Amino-5-chloro-2-methoxy-N-[2-(diethylamino)ethyl]benzamide dihydrochloride; NSC 339024; Clebopride HCl; Clebopride Dihydrochloride Salt; Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Chloro-n-[2-(Diethylamino)Ethyl]-2-Methoxybenzamide Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for pharmaceutical R&D and intermediate use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.