Description

2-(Trifluoroacetyl)Pyrrole is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a pyrrole ring and a highly electron-withdrawing trifluoroacetyl group, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the stability imparted by the fluorine atoms.
• Material Science Research: Serves as a building block for creating advanced organic materials, including conductive polymers, organic semiconductors, and liquid crystals.
• Medicinal Chemistry & Drug Discovery: Employed in high-throughput screening and the construction of diverse compound libraries for hit identification and lead optimization.
• Fluorine Chemistry Studies: An important reagent for investigating the effects of fluorine substitution on the reactivity and biological activity of heterocyclic compounds.
• Chemical Research & Development: Used as a standard or reference compound in analytical method development and synthetic route exploration.

Basic Information

Product Name	2-(Trifluoroacetyl)Pyrrole
CAS No.	2557-70-2
Molecular Formula	C6H4F3NO
Molecular Weight	163.10 g/mol
Synonyms	1H-Pyrrole-2-carboxaldehyde, 2,2,2-trifluoro-1-(1H-pyrrol-2-yl)ethanone; 2,2,2-Trifluoro-1-(1H-pyrrol-2-yl)ethan-1-one; 1-(1H-Pyrrol-2-yl)-2,2,2-trifluoroethanone; 2-Trifluoroacetylpyrrole; α,α,α-Trifluoro-2-pyrrolyl methyl ketone; 2-Pyrrolyl trifluoromethyl ketone; TFAP
EINECS	219-876-4

Quality Control

Our 2-(Trifluoroacetyl)Pyrrole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.