Description

3-Fluoro-4-Bromopyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and bromine substituents, makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies for applications in medicinal chemistry, agrochemical development, and materials science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and molecular probes for biochemical and diagnostic research.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.

Basic Information

Item	Details
Product Name	3-Fluoro-4-Bromopyridine
CAS No.	2546-52-3
Molecular Formula	C5H3BrFN
Molecular Weight	175.99 g/mol
Synonyms	4-Bromo-3-fluoropyridine; 3-Fluoro-4-bromopyridine; 4-Bromo-3-fluoro-pyridine; Pyridine, 4-bromo-3-fluoro-; 3-Fluoropyridine-4-bromide; 2546-52-3 (CAS); 3-Fluoro-4-bromo-pyridine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Bromopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0% (Standard Grade)
Purity (GC)	≥98.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.