Description

Lincomycin B is a lincosamide antibiotic, a key intermediate and reference standard in the research and development of antibacterial agents. Its significance lies in its structural relationship to the clinically important antibiotic Lincomycin, making it a critical compound for analytical studies, impurity profiling, and pharmacological research. This product is essential for pharmaceutical R&D laboratories, quality control departments, and academic institutions focused on antibiotic development and microbiological studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity testing of Lincomycin and its derivatives in accordance with pharmacopeial methods (e.g., USP, EP).
• Antibiotic Research & Development: Serves as a crucial intermediate and analytical standard in the synthesis and study of novel lincosamide antibiotics and their structure-activity relationships.
• Microbiological Studies: Employed in laboratory research to study bacterial resistance mechanisms, antibiotic potency, and the mode of action of lincosamide-class drugs.
• Quality Control & Impurity Profiling: Essential for HPLC, LC-MS, and other analytical methods to quantify and qualify Lincomycin B as a related substance in bulk drug substances and finished pharmaceutical products.
• Academic & Institutional Research: Used in universities and research institutes for teaching and investigative projects in medicinal chemistry, pharmacology, and analytical chemistry.

Basic Information

Product Name	Lincomycin B
CAS No.	2520-24-3
Molecular Formula	C18H34N2O6S
Molecular Weight	406.54 g/mol
Synonyms	Lincomycin B; (2S,4R)-1-Methyl-4-propyl-N-[(1R,2R,3S,4S,6R)-2,4,6-trideoxy-2-[(2R,3R,4S,6R)-3,4-dihydroxy-6-methylsulfanyloxan-2-yl]amino-3-O-methyl-α-L-threo-hexopyranosyl]pyrrolidine-2-carboxamide; U-10149; Antibiotic U-10149; NSC-112682; Lincomycin B Hydrochloride (salt form)
EINECS	219-759-4

Quality Control

Our Lincomycin B is produced and handled under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances as determined by advanced analytical techniques including HPLC and spectroscopic methods. We support compliance needs for pharmaceutical research with materials suitable for use as reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.