Description

4-Amino-3-Fluoropyridine is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique chemical structure, which introduces both an amino group and a fluorine atom onto the pyridine ring, enabling precise molecular modifications. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the design of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Utilized to create fluorinated analogs of bioactive molecules for metabolic pathway studies and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom chemical synthesis services catering to diverse R&D projects.

Basic Information

Product Name	4-Amino-3-Fluoropyridine
CAS No.	2447-88-3
Molecular Formula	C5H5FN2
Molecular Weight	112.11 g/mol
Synonyms	3-Fluoro-4-aminopyridine; 3-Fluoro-pyridin-4-ylamine; 4-Pyridinamine, 3-fluoro-; 3-Fluoro-4-pyridinylamine; 4-Amino-3-fluoropyridine; 3-Fluoropyridin-4-amine; 4-Amino-3-fluoro-pyridine; 3-Fluoro-4-aminopyridine
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Fluoropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.