Description

(4Alpha,5Alpha,17Beta)-4,17-Dimethylspiro[Androstane-3,3'-[3H]Diazirin]-17-Ol CAS NO 2398-56-3 is a high-purity, synthetic steroid derivative featuring a photoactivatable diazirine group. This compound is specifically engineered for advanced biochemical research, serving as a critical tool for covalent cross-linking and photoaffinity labeling studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on elucidating steroid hormone receptor interactions and metabolic pathways.

Application

• Photoaffinity Labeling Probes: Acts as a key intermediate for synthesizing probes to study steroid-protein interactions and receptor binding sites.
• Biochemical Research: Used in the investigation of androgen and steroid hormone receptor mechanisms and signal transduction pathways.
• Pharmaceutical Development: Serves as a specialized building block in the discovery and development of novel therapeutic agents targeting hormonal systems.
• Metabolic Pathway Analysis: Employed as a tracer compound to study steroid metabolism and biotransformation in biological systems.
• Proteomics and Structural Biology: Facilitates the identification and characterization of unknown steroid-binding proteins through covalent cross-linking techniques.

Basic Information

Product Name	(4Alpha,5Alpha,17Beta)-4,17-Dimethylspiro[Androstane-3,3'-[3H]Diazirin]-17-Ol
CAS No.	2398-56-3
Molecular Formula	C₂₁H₃₂N₂O
Molecular Weight	328.50 g/mol
Synonyms	4,17-Dimethylspiro[androstane-3,3'-[3H]diazirin]-17-ol; 17β-Hydroxy-4,17-dimethylspiro[androstane-3,3'-diazirine]; 4,17-Dimethylspiro[5α-androstane-3,3'-diazirine]-17β-ol; Diazirine-labeled Androstane Derivative; Photoactivatable Androstane; CAS 2398-56-3
EINECS	Contact for details

Quality Control

Every batch of (4Alpha,5Alpha,17Beta)-4,17-Dimethylspiro[Androstane-3,3'-[3H]Diazirin]-17-Ol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.