Description

3-Fluoro-1H-Pyrrole is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its ability to introduce fluorine atoms and the pyrrole scaffold into target molecules, enabling the fine-tuning of electronic properties, lipophilicity, and metabolic stability. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, organic semiconductors, and conductive materials.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: A fundamental reagent for academic and industrial research into new fluorination reactions and heterocyclic chemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fluorinated fine chemicals and specialty dyes.

Basic Information

Product Name	3-Fluoro-1H-Pyrrole
CAS No.	2358-35-2
Molecular Formula	C4H4FN
Molecular Weight	85.08 g/mol
Synonyms	3-Fluoropyrrole; 3-Fluoro-1H-pyrrole; 1H-Pyrrole, 3-fluoro-; 3-Fluoropyrrole, 1H-Pyrrole, 3-fluoro-; 3-Fluoro-pyrrole; 3-Fluor-1H-pyrrol; 3-Fluoro-1H-azole
EINECS	Contact for details

Quality Control

Our 3-Fluoro-1H-Pyrrole is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system supports development from research to commercial scale under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and away from heat sources and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.