Description

1-Bromo-4-(Bromodifluoromethyl)Benzene is a versatile and highly functionalized aromatic building block. This compound is valued for its dual reactive sites, enabling its use as a key intermediate in the synthesis of complex organic molecules. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing difluoromethyl or aryl bromide motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Acts as a building block for creating advanced organic electronic materials, including charge-transport layers and light-emitting compounds.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Polymer Modification: Used to introduce bromine and difluoromethyl functional groups into polymer backbones to alter physical and chemical properties.
• Cross-Coupling Reactions: The aryl bromide moiety makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	1-Bromo-4-(Bromodifluoromethyl)Benzene
CAS No.	2358-32-9
Molecular Formula	C7H4Br2F2
Molecular Weight	305.91 g/mol
Synonyms	4-Bromo-α,α-difluorobenzyl Bromide; p-Bromo-α,α-difluorobenzyl Bromide; 1-Bromo-4-(dibromomethyl)benzene (common misnomer); (4-Bromophenyl)difluoromethyl Bromide; Benzene, 1-bromo-4-(bromodifluoromethyl)-; α,α-Difluoro-4-bromobenzyl Bromide; p-Bromo-α,α-difluorotoluene bromide
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(Bromodifluoromethyl)Benzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.