Description

4-(Bromodifluoromethyl)-1-(Difluoromethyl)Benzene is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromodifluoromethyl and difluoromethyl substituents, makes it a versatile precursor for introducing fluorinated motifs into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries. Its application is critical for the development of novel compounds with enhanced metabolic stability, bioavailability, and specific biological activity.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) with fluorinated aromatic rings, aiming to improve drug potency and pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with unique surface properties or chemical resistance.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated components for electronic display technologies and organic light-emitting diodes (OLEDs).
• Fluorine Chemistry Research: An essential reagent in academic and industrial R&D for studying nucleophilic substitution reactions and developing new fluorination methodologies.
• Positron Emission Tomography (PET) Tracer Development: Potential use as a synthon for creating fluorine-18 labeled radiopharmaceuticals for medical imaging.

Basic Information

Item	Detail
Product Name	4-(Bromodifluoromethyl)-1-(Difluoromethyl)Benzene
CAS No.	2250-36-4
Molecular Formula	C9H5BrF4
Molecular Weight	269.04 g/mol
Synonyms	1-Bromo-4-(bromodifluoromethyl)benzene (common misnomer); α,α-Difluoro-4-(bromodifluoromethyl)toluene; 1-(Difluoromethyl)-4-(bromodifluoromethyl)benzene; p-(Bromodifluoromethyl)benzylidene difluoride; Benzene, 1-(bromodifluoromethyl)-4-(difluoromethyl)-; 4-Bromodifluoromethyl-α,α-difluorotoluene
EINECS	Contact for details

Quality Control

Every batch of 4-(Bromodifluoromethyl)-1-(Difluoromethyl)Benzene is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including GC, HPLC, and NMR to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. Handle and store under an inert atmosphere if prolonged storage is required to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.