Description

4-Amino-3-Fluoropyridine is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino group and a fluorine atom on the pyridine ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functional polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for modifying peptides and other biomolecules to study biological interactions and pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Amino-3-Fluoropyridine
CAS No.	2247-88-3
Molecular Formula	C5H5FN2
Molecular Weight	112.11 g/mol
Synonyms	3-Fluoro-4-aminopyridine; 3-Fluoro-pyridin-4-ylamine; 4-Pyridinamine, 3-fluoro-; 3-Fluoro-4-pyridinylamine; 4-Amino-3-fluoropyridine; 3-Fluoropyridin-4-amine; 3-Fluoro-4-aminopyridine; 4-Amino-3-fluoro-pyridine
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Fluoropyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.