Description

6-(Sulfonyloxy)Melatonin is a chemically modified derivative of the hormone melatonin, designed for enhanced stability and reactivity in synthetic applications. This compound serves as a crucial advanced pharmaceutical intermediate, enabling the development of novel therapeutic agents and research chemicals. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in neuroendocrine research and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel melatonin receptor agonists and related neuroactive compounds.
• Research & Development: Used in academic and industrial labs for studying sleep-wake cycle mechanisms and developing chronobiological therapies.
• Prodrug Synthesis: Acts as a sulfonate ester precursor for creating prodrugs with improved bioavailability and targeted delivery.
• Bioconjugation: Employed in the preparation of labeled analogs and conjugates for biochemical and pharmacological studies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in regulatory testing.

Basic Information

Item	Detail
Product Name	6-(Sulfonyloxy)Melatonin
CAS No.	2208-40-4
Molecular Formula	C13H16N2O4S
Molecular Weight	296.34 g/mol
Synonyms	6-Hydroxymelatonin Sulfonate; 6-O-Sulfomelatonin; N-[2-(6-Sulfonyloxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide; Melatonin 6-sulfate; 6-Sulfatoxymelatonin; 6-SM; aMT6s; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 6-(Sulfonyloxy)Melatonin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.