Description

Orotidine 5'-Monophosphate (OMP) is a key nucleotide intermediate in the de novo biosynthesis of pyrimidines. This compound matters as a critical biochemical reagent for studying nucleotide metabolism, enzyme kinetics, and cellular signaling pathways. It is primarily needed by research institutions, pharmaceutical developers, and diagnostic manufacturers for applications in enzymology, molecular biology, and as a reference standard.

Application

• Biochemical Research: Essential substrate for studying orotidine 5'-monophosphate decarboxylase (OMP decarboxylase) and other enzymes in the pyrimidine synthesis pathway.
• Pharmaceutical Development: Used in research for developing inhibitors targeting nucleotide metabolism, relevant for anticancer and antiviral drug discovery.
• Diagnostic Reagent Manufacturing: Serves as a component or calibrator in enzymatic assay kits for metabolic disorder diagnostics.
• Enzymology Studies: Critical for investigating enzyme mechanisms, catalytic efficiency, and inhibition studies in vitro.
• Reference Standard: High-purity grade used as a certified reference material (CRM) for analytical method development and validation in QC laboratories.
• Cell Culture & Metabolism: Utilized in cell-based assays to study pyrimidine salvage pathways and nucleotide pool regulation.

Basic Information

Product Name	Orotidine 5'-Monophosphate
CAS No.	2149-82-8
Molecular Formula	C10H13N2O11P
Molecular Weight	368.19 g/mol
Synonyms	Orotidine 5'-Phosphate; Orotidylic Acid; 5'-OMP; 1-(5-O-Phosphono-β-D-ribofuranosyl)orotic Acid; Orotidine Monophosphate; 6-Carboxyuridine 5'-Monophosphate; Uridine-6-carboxylic acid 5'-phosphate
EINECS	218-408-9

Quality Control

Our Orotidine 5'-Monophosphate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-grade research specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption. Keep the container in a dry, cool environment after use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	2.0 - 4.0
Endotoxin (LAL)	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.