Description

1,2,2,2-Tetrafluoroethylsulfonyl Fluoride is a versatile and highly reactive fluorinated sulfonyl fluoride intermediate. Its unique structure makes it a critical building block for introducing the tetrafluoroethylsulfonyl group into target molecules, enabling the synthesis of advanced materials and specialty chemicals. This compound is essential for R&D and production in the pharmaceutical, agrochemical, and advanced polymer industries, where its properties can impart enhanced stability, lipophilicity, and specific reactivity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in sulfonamide-based drugs.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Polymer & Material Science: Serves as a monomer or modifier for producing high-performance fluoropolymers with exceptional chemical and thermal resistance.
• Liquid Crystal & Electronic Chemicals: Employed in the synthesis of fluorinated components for liquid crystal displays (LCDs) and dielectric materials.
• Surfactant & Surface Treatment Agent: Building block for specialty fluorosurfactants and surface modifiers that lower surface energy.
• Organic Synthesis Reagent: A valuable reagent for introducing sulfonyl fluoride functional groups in complex organic molecule construction.

Basic Information

Product Name	1,2,2,2-Tetrafluoroethylsulfonyl Fluoride
CAS No.	2127-74-4
Molecular Formula	C2HF5O2S
Molecular Weight	184.08 g/mol
Synonyms	2,2,2-Tetrafluoroethanesulfonyl Fluoride; Tetrafluoroethylsulfonyl Fluoride; 1,1,2,2-Tetrafluoro-2-(fluorosulfonyl)ethane; Perfluoroethylsulfonyl Fluoride; FESF; Tetrafluoroethanesulfonyl Fluoride; Ethanesulfonyl fluoride, 1,1,2,2-tetrafluoro-
EINECS	218-341-5

Quality Control

Our 1,2,2,2-Tetrafluoroethylsulfonyl Fluoride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.