Description

Demethylchlorpromazine Sulfoxide is a key pharmaceutical intermediate and reference standard of significant importance in research and development. Its primary value lies in its role as a metabolite and precursor in the synthesis of phenothiazine-derived compounds, which are critical in medicinal chemistry. This product is essential for pharmaceutical manufacturers, analytical laboratories, and academic researchers focused on neuropharmacology, drug metabolism studies, and quality control of related active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of phenothiazine-based antipsychotic and neuroleptic agents.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) testing in pharmaceutical manufacturing.
• Metabolite Studies: Employed in pharmacokinetic and drug metabolism research to understand the biotransformation pathways of chlorpromazine and related drugs.
• Biochemical Research: Serves as a tool compound in neuroscience and pharmacology research to study receptor interactions and mechanisms of action.
• Impurity Standard: Used to identify, quantify, and control related substance impurities in bulk active pharmaceutical ingredients (APIs).
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting medicinal chemistry and drug discovery programs.

Basic Information

Product Name	Demethylchlorpromazine Sulfoxide
CAS No.	2037-58-3
Molecular Formula	C17H19ClN2OS
Molecular Weight	334.86 g/mol
Synonyms	2-Chloro-10-[3-(methylamino)propyl]phenothiazine 5-Oxide; Desmethylchlorpromazine Sulfoxide; Norchlorpromazine Sulfoxide; 5-Oxido-2-chloro-10-[3-(methylamino)propyl]phenothiazine; Demethylchlorpromazine S-Oxide; N-Desmethylchlorpromazine Sulfoxide; Chlorpromazine Sulfoxide Impurity; Phenothiazine-5-oxide derivative
EINECS	Contact for details

Quality Control

Our Demethylchlorpromazine Sulfoxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA). Specifications are aligned with the requirements for pharmaceutical intermediates and reference standards, supporting compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.