Description

Bomedemstat CAS NO 1990504-72-7 is a potent and selective investigational small molecule inhibitor of lysine-specific demethylase 1 (LSD1), a key epigenetic regulator. This compound is of significant interest for its potential in modulating gene expression and cellular differentiation pathways. It is primarily utilized by pharmaceutical research and development organizations engaged in oncology and hematology drug discovery programs.

Application

• Oncology Research: Investigated as a potential therapeutic agent for various cancers, including acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), and small cell lung cancer (SCLC).
• Hematology Drug Discovery: Used in preclinical studies targeting disorders of the blood and bone marrow where LSD1 inhibition shows promise.
• Epigenetics Research: Serves as a critical tool compound for studying the role of LSD1 and histone demethylation in cellular processes and disease states.
• Pharmaceutical Intermediate: Employed in the synthesis and development of novel LSD1-targeting drug candidates under clinical evaluation.
• Biochemical Assay Development: Used as a reference standard in high-throughput screening (HTS) and enzymatic assays to identify and characterize new epigenetic modulators.

Basic Information

Product Name	Bomedemstat
CAS No.	1990504-72-7
Molecular Formula	C₂₀H₂₀F₃N₅O₂
Molecular Weight	419.40 g/mol
Synonyms	IMG-7289; Bomedemstatum; (1R,2S)-2-(4-((4-((trans-2-(4-(Trifluoromethyl)phenyl)cyclopropyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropane-1-carboxylic acid; LSD1 Inhibitor IMG-7289; IMG 7289
EINECS	Contact for details

Quality Control

Our Bomedemstat is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular ion [M+H]+
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.