Description

(R)-1-(2-Fluoropyridin-4-Yl)Ethanamine Hydrochloride is a high-purity chiral amine building block, essential for the synthesis of advanced pharmaceutical intermediates and active pharmaceutical ingredients (APIs). Its value lies in providing a stereochemically defined, fluorinated pyridine core, which is critical for modulating the biological activity, metabolic stability, and physicochemical properties of drug candidates. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutics, particularly in areas such as oncology, central nervous system (CNS) disorders, and anti-infectives.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel small-molecule drugs.
• API Synthesis: Used in the construction of complex molecules for potential therapeutic agents targeting various diseases.
• Asymmetric Catalysis Research: Serves as a ligand precursor or a chiral auxiliary in the development of new catalytic systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Agrochemical Research: Potential building block for the development of new, more effective crop protection agents.
• Material Science: Can be investigated for incorporation into specialty polymers or advanced organic materials.

Basic Information

Product Name	(R)-1-(2-Fluoropyridin-4-Yl)Ethanamine Hydrochloride
CAS No.	1956436-88-6
Molecular Formula	C7H10ClFN2
Molecular Weight	176.62 g/mol
Synonyms	(R)-1-(2-Fluoro-4-pyridinyl)ethanamine hydrochloride; (R)-1-(2-Fluoropyridin-4-yl)ethan-1-amine hydrochloride; (R)-α-Methyl-2-fluoro-4-pyridinemethanamine hydrochloride; (R)-2-Fluoro-4-(1-aminoethyl)pyridine hydrochloride; (R)-4-(1-Aminoethyl)-2-fluoropyridine hydrochloride; (R)-1-(2-Fluoro-4-pyridyl)ethylamine hydrochloride; (R)-1-(2-Fluoropyridin-4-yl)ethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(2-Fluoropyridin-4-Yl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.