Description

1-(3-Fluoroquinolin-6-Yl)Ethanone is a specialized fluorinated quinoline derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel pharmaceuticals and agrochemicals, where the fluorine atom and ketone moiety are key for modulating biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in oncology, antimicrobial, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorinated quinoline scaffold for enhanced efficacy and environmental profile.
• Material Science: Serves as a building block for creating advanced organic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Synthesis: Employed in academic and industrial research laboratories for method development and as a versatile substrate in cross-coupling and functionalization reactions.
• Ligand and Catalyst Development: Utilized in the design of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-(3-Fluoroquinolin-6-Yl)Ethanone
CAS No.	1956331-78-4
Molecular Formula	C11H8FNO
Molecular Weight	189.19 g/mol
Synonyms	6-Acetyl-3-fluoroquinoline; 3-Fluoro-6-acetylquinoline; 1-(3-Fluoro-6-quinolyl)ethanone; Ethanone, 1-(3-fluoro-6-quinolinyl)-; 3-Fluoroquinoline-6-carbaldehyde (common misnomer check); FQAE; 3-F-6-AcQ
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoroquinolin-6-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical data. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.