Description

(6-Fluoropyridin-3-Yl)Methanamine Dihydrochloride is a high-purity, fluorinated pyridine derivative building block essential for advanced pharmaceutical and agrochemical research. Its core value lies in its role as a versatile amine synthon, enabling the introduction of a functionalized pyridine scaffold into complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and CNS-targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the fluoropyridine moiety.
• Chemical Biology & Proteomics: Serves as a valuable probe or linker in the development of chemical tools for studying biological systems.
• Material Science Precursor: Potential use in the synthesis of specialized ligands for catalysts or functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	(6-Fluoropyridin-3-Yl)Methanamine Dihydrochloride
CAS No.	1955506-73-6
Molecular Formula	C6H8F1N2 · 2HCl
Molecular Weight	207.06 g/mol (Free base: 126.14 g/mol)
Synonyms	1-(6-Fluoropyridin-3-yl)methanamine dihydrochloride; (6-Fluoro-3-pyridinyl)methanamine dihydrochloride; 3-(Aminomethyl)-6-fluoropyridine dihydrochloride; 6-Fluoronicotinylamine dihydrochloride; 5-(Aminomethyl)-2-fluoropyridine dihydrochloride; 2-Fluoro-5-(aminomethyl)pyridine dihydrochloride; (6-Fluoropyridin-3-yl)methylamine hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our (6-Fluoropyridin-3-Yl)Methanamine Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay (Titration)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.