Description

Ethyl 3-(3-Fluoropyridin-2-Yl)Acrylate is a high-value fluorinated pyridine derivative and acrylate ester, serving as a critical building block in advanced organic synthesis. This compound is essential for introducing both a fluoropyridine moiety and an activated acrylate functionality into target molecules, enabling the development of novel compounds with tailored properties. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the fluoropyridine group can enhance biological activity and environmental stability.
• Material Science Research: Employed as a monomer or cross-linker precursor in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or activity-based probes for studying biological systems and enzyme functions.
• Library Synthesis for Drug Discovery: A versatile scaffold for generating diverse compound libraries via parallel synthesis and combinatorial chemistry techniques.

Basic Information

Product Name	Ethyl 3-(3-Fluoropyridin-2-Yl)Acrylate
CAS No.	1951451-53-8
Molecular Formula	C10H10FNO2
Molecular Weight	195.19 g/mol
Synonyms	Ethyl (E)-3-(3-Fluoropyridin-2-yl)acrylate; (E)-Ethyl 3-(3-fluoropyridin-2-yl)acrylate; 2-Propenoic acid, 3-(3-fluoro-2-pyridinyl)-, ethyl ester; Ethyl (E)-3-(3-fluoro-2-pyridinyl)-2-propenoate; 3-(3-Fluoropyridin-2-yl)acrylic acid ethyl ester; 2-Fluoro-3-(2-ethoxycarbonylvinyl)pyridine; Ethyl 3-(3-fluoro-2-pyridyl)acrylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-(3-Fluoropyridin-2-Yl)Acrylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and compliance with REACH regulations ensures a reliable supply for global research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (E/Z Ratio)	≥ 95:5 (E/Z)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.