Description

Dot1L-In-2 is a high-purity, small-molecule chemical compound with the CAS number 1940206-71-2, designed for advanced research and development applications. This compound is valued for its specific biochemical activity, making it a critical reagent in the exploration of novel therapeutic pathways and biological mechanisms. It is primarily sought after by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on epigenetics, oncology, and neurological disease research.

Application

• Epigenetic Research: Used as a potent and selective inhibitor in studies targeting histone methylation and related biological processes.
• Drug Discovery & Development: Serves as a key biochemical tool for target validation, high-throughput screening, and lead optimization in pharmaceutical R&D.
• Oncology Research: Employed in cellular and in-vivo models to investigate the role of specific epigenetic modifiers in cancer progression and treatment resistance.
• Neuroscience Studies: Applied in research exploring the epigenetic basis of neurological disorders and cognitive function.
• Biochemical Assay Development: Acts as a reference standard in developing and validating sensitive assays for enzymatic activity.
• Academic Research: Utilized in university and institutional labs for fundamental research in cell biology and molecular genetics.

Basic Information

Product Name	Dot1L-In-2
CAS No.	1940206-71-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dot1L Inhibitor 2; DOT1L-IN-2; 1940206-71-2; Disruptor of Telomeric Silencing 1-Like Inhibitor 2; Histone Methyltransferase DOT1L Inhibitor; SGC0946 (related compound class); Epigenetic inhibitor compound
EINECS	Contact for details

Quality Control

Every batch of Dot1L-In-2 is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.