Description

Irak4 Inhibitor CAS NO 1931994-80-7 is a potent and selective small molecule compound designed to target and inhibit the Interleukin-1 Receptor-Associated Kinase 4 (IRAK4), a key signaling node in innate immune pathways. This targeted inhibition makes it a critical research tool and a promising candidate for therapeutic development in inflammatory and autoimmune diseases. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on immunology, oncology, and chronic inflammatory conditions.

Application

• Biomedical Research: A vital pharmacological tool for studying the role of IRAK4 in Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signaling pathways.
• Drug Discovery & Preclinical Development: Serves as a reference compound or lead molecule for developing novel therapeutics targeting IRAK4 in autoimmune disorders like rheumatoid arthritis and lupus.
• Oncology Research: Investigated for its potential role in modulating the tumor microenvironment and in cancers driven by chronic inflammation or MyD88 mutations.
• Inflammatory Disease Models: Used in vitro and in vivo to validate IRAK4 as a target and to assess efficacy in models of sepsis, psoriasis, and other inflammatory conditions.
• Mechanistic Studies: Enables detailed exploration of downstream NF-κB and MAPK pathway activation following innate immune stimulation.

Basic Information

Item	Details
Product Name	Irak4 Inhibitor CAS NO 1931994-80-7
CAS No.	1931994-80-7
Molecular Formula	C₂₀H₂₀N₆O₂
Molecular Weight	376.41 g/mol
Synonyms	IRAK-4 Inhibitor; IRAK4 Inhibitor; 1931994-80-7; 4-[(2S)-2-[[4-(4-Fluorophenoxy)phenyl]sulfonylamino]-3-hydroxypropyl]-N,N-dimethyl-1H-pyrrole-2-carboxamide; BAY 1830839; Compound 26; (2S)-2-[[[4-(4-Fluorophenoxy)phenyl]sulfonyl]amino]-3-[4-(dimethylcarbamoyl)-1H-pyrrol-2-yl]propan-1-ol
EINECS	Contact for details

Quality Control

Our Irak4 Inhibitor is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. The compound is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a controlled, dry environment to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.