Description

Z-Le(Ome)Td(Ome) Fluoromethylketone is a specialized, high-purity fluorinated peptide derivative designed for advanced proteomics and biochemical research. This compound serves as a critical building block and protease inhibitor, enabling precise control over enzymatic activity in complex biological systems. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutics and diagnostic tools.

Application

• Protease Inhibition Studies: Acts as a potent and selective inhibitor for studying cysteine and serine protease mechanisms.
• Pharmaceutical Research: A key intermediate in the synthesis of peptide-based drug candidates and targeted inhibitors.
• Biochemical Assay Development: Used to develop and validate high-throughput screening assays for drug discovery.
• Proteomics & Cell Biology: Enables the investigation of specific protease roles in cellular pathways, apoptosis, and disease states.
• Chemical Biology Tool: Employed in activity-based protein profiling (ABPP) to identify and characterize enzyme function.
• Reference Standard: Serves as a certified reference material for analytical method development and quality control in API synthesis.

Basic Information

Product Name	Z-Le(Ome)Td(Ome) Fluoromethylketone
CAS No.	1926163-60-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Z-Leu-Tyr(OMe)-FMK; Z-Leu-Tyr(OMe)-Fluoromethyl Ketone; Benzyloxycarbonyl-Leucyl-Tyrosine(OMe) Fluoromethyl Ketone; Caspase Inhibitor (broad-spectrum); Peptidyl Fluoromethyl Ketone Inhibitor; Z-L-Y(OMe)-FMK; FMK-based Protease Inhibitor; Z-Leu-Tyr(OMe)-CH2F
EINECS	Contact for details

Quality Control

Our Z-Le(Ome)Td(Ome) Fluoromethylketone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.