Description

Z-Val-Arg-Pro-Dl-Arg-Fluoromethylketone Trifluoroacetate Salt is a high-purity, synthetic peptide derivative designed as a potent and selective protease inhibitor. This compound is critical for biochemical research and pharmaceutical development, particularly in the study of enzyme kinetics and the design of therapeutic agents. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical developers focused on cardiovascular, inflammatory, and oncological pathways.

Application

• Protease Inhibition Research: Serves as a key biochemical tool for studying the activity and mechanism of specific serine or cysteine proteases.
• Drug Discovery & Development: Used as a reference standard or lead compound in the design of novel therapeutic inhibitors for diseases involving dysregulated proteolytic activity.
• Biochemical Assay Development: Employed in the validation and calibration of high-throughput screening (HTS) assays to identify new inhibitor candidates.
• Academic & Pharmaceutical R&D: Essential for basic research in enzymology, cell signaling pathways, and the pathophysiology of conditions like thrombosis and cancer metastasis.
• Quality Control Standard: Acts as a certified reference material (CRM) for analytical method development and quality assurance in peptide synthesis.

Basic Information

Product Name	Z-Val-Arg-Pro-Dl-Arg-Fluoromethylketone Trifluoroacetate Salt
CAS No.	1926163-57-6
Molecular Formula	C34H54F3N11O9
Molecular Weight	817.86 g/mol
Synonyms	Z-VRPR-FMK TFA Salt; Boc-Val-Arg-Pro-Arg-Fluoromethylketone TFA; Z-Val-Arg-Pro-Arg-FMK TFA; Benzyloxycarbonyl-Val-Arg-Pro-D-Arg-Fluoromethyl Ketone Trifluoroacetate; Protease Inhibitor 1926163-57-6; FMK-based Peptide Inhibitor; Val-Arg-Pro-Arg-Fluoromethylketone derivative; Z-VRPR(D-Arg)-FMK TFA
EINECS	Contact for details

Quality Control

Our Z-Val-Arg-Pro-Dl-Arg-Fluoromethylketone Trifluoroacetate Salt is manufactured under stringent conditions to ensure batch-to-batch consistency and high chemical purity, suitable for sensitive research applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC and MS, are validated to provide reliable specifications for the research community.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be kept under desiccant in the original container. Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.