Description

2-((1S,4S)-4-(6-Fluoroquinolin-4-Yl)Cyclohexyl)Aceticacid is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and fluorinated quinoline core structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of targeted small-molecule drugs. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific enzymatic pathways or receptors.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the research and scale-up of new Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used extensively in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Preclinical & Clinical Trial Material: Supplied for the production of materials required for preclinical studies and clinical trial batches under GMP guidelines.
• Chemical Biology Probes: Employed in the development of chemical probes for investigating biological mechanisms and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.

Basic Information

Product Name	2-((1S,4S)-4-(6-Fluoroquinolin-4-Yl)Cyclohexyl)Aceticacid
CAS No.	1923846-51-8
Molecular Formula	C₁₇H₁₈FNO₂
Molecular Weight	287.33 g/mol
Synonyms	(1S,4S)-2-[4-(6-Fluoro-4-quinolyl)cyclohexyl]acetic acid; 2-[(1S,4S)-4-(6-Fluoroquinolin-4-yl)cyclohexyl]acetic Acid; 2-((1S,4S)-4-(6-Fluoro-4-quinolinyl)cyclohexyl)acetic acid; 1923846-51-8; (1s,4s)-4-(6-Fluoroquinolin-4-yl)cyclohexaneacetic acid; 2-[(1S,4S)-4-(6-Fluoroquinolin-4-yl)cyclohexyl]ethanoic acid
EINECS	Contact for details

Quality Control

Our 2-((1S,4S)-4-(6-Fluoroquinolin-4-Yl)Cyclohexyl)Aceticacid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided and can be tailored to meet specific client or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product should be handled under inert conditions if necessary to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (1S,4S)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.