Description

1-(3-Fluoropyridin-4-yl)ethanone is a high-purity fluorinated pyridine derivative, a crucial building block in modern organic synthesis. Its value lies in its unique molecular structure, which serves as a versatile intermediate for constructing complex molecules in advanced research and development. This compound is primarily needed by pharmaceutical, agrochemical, and material science industries for applications in drug discovery, crop protection, and specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for synthesizing functionalized ligands, liquid crystals, and organic electronic materials.
• Chemical Biology: Employed as a probe or labeling agent in biochemical research due to its reactive ketone group.
• Custom Synthesis: A fundamental starting material for contract research organizations (CROs) and CDMOs engaged in custom and scale-up synthesis projects.

Basic Information

Product Name	1-(3-Fluoropyridin-4-yl)ethanone
CAS No.	1905413-57-1
Molecular Formula	C7H6FNO
Molecular Weight	139.13 g/mol
Synonyms	4-Acetyl-3-fluoropyridine; 3-Fluoro-4-acetylpyridine; 1-(3-Fluoro-4-pyridinyl)ethanone; 3-Fluoropyridin-4-yl methyl ketone; 4-Acetyl-3-fluoro-pyridine; Ethanone, 1-(3-fluoro-4-pyridinyl)-; 1-(3-Fluoropyridin-4-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoropyridin-4-yl)ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.