Description

(3S,4S)-3-Fluorooxan-4-Amine Hcl CAS NO 1895912-87-4 is a high-purity chiral amine hydrochloride salt, characterized by its stereospecific fluorine substitution on the oxane (tetrahydropyran) ring. This compound is a critical chiral building block and intermediate in modern pharmaceutical research and development, offering precise control over molecular geometry for enhanced biological activity. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new small-molecule drugs, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced, stereospecific pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Incorporated into peptide analogs to modulate stability, bioavailability, and receptor binding.
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme mechanisms and biological pathways.
• Process Chemistry: Used in route scouting and optimization for the scalable manufacturing of complex target molecules.

Basic Information

Product Name	(3S,4S)-3-Fluorooxan-4-Amine Hydrochloride
CAS No.	1895912-87-4
Molecular Formula	C5H11ClFNO
Molecular Weight	155.60 g/mol
Synonyms	(3S,4S)-3-Fluorooxan-4-amine hydrochloride; (3S,4S)-3-Fluorotetrahydropyran-4-amine HCl; 4-Amino-3-fluorotetrahydropyran hydrochloride, (3S,4S)-; (3S,4S)-3-Fluoro-4-aminotetrahydropyran hydrochloride; 3-Fluorooxan-4-amine hydrochloride, (3S,4S)-; (3S,4S)-4-Amino-3-fluorotetrahydropyran hydrochloride; (3S,4S)-3-Fluoro-THP-4-amine HCl
EINECS	Contact for details

Quality Control

Our (3S,4S)-3-Fluorooxan-4-Amine HCl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.