Description

3-Methyl-2-Trifluoromethylpyridine-5-Boronic Acid is a high-value, multi-functional boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex molecular architectures with precision. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and inhibitors for studying enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: Essential for research organizations and CDMOs (Contract Development and Manufacturing Organizations) engaged in custom synthesis projects.

Basic Information

Product Name	3-Methyl-2-Trifluoromethylpyridine-5-Boronic Acid
CAS No.	1889221-03-7
Molecular Formula	C8H7BF3NO2
Molecular Weight	217.96 g/mol
Synonyms	(5-Borono-3-methyl-2-(trifluoromethyl)pyridine; 3-Methyl-2-(trifluoromethyl)pyridine-5-boronic acid; 2-(Trifluoromethyl)-5-pyridineboronic acid, 3-methyl-; 5-Borono-3-methyl-2-trifluoromethylpyridine; 3-Methyl-2-trifluoromethyl-5-pyridineboronic acid; Boronic acid, B-[3-methyl-2-(trifluoromethyl)-5-pyridinyl]-; [3-Methyl-2-(trifluoromethyl)pyridin-5-yl]boronic acid
EINECS	Contact for details

Quality Control

Our 3-Methyl-2-Trifluoromethylpyridine-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.