Description

6-Bromo-2,4-difluoro-3-methylbenzaldehyde is a versatile and highly functionalized aromatic aldehyde building block. Its molecular structure, featuring bromo, fluoro, and aldehyde substituents, makes it a critical intermediate for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for use in medicinal chemistry, specifically in the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents. Its precise reactivity profile enables the introduction of multiple halogen handles for further selective derivatization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the difluoro and bromo substituents contribute to biological activity and metabolic stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic core.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	6-Bromo-2,4-difluoro-3-methylbenzaldehyde
CAS No.	1879026-17-1
Molecular Formula	C8H5BrF2O
Molecular Weight	235.03 g/mol
Synonyms	3-Methyl-6-bromo-2,4-difluorobenzaldehyde; 2,4-Difluoro-6-bromo-3-methylbenzaldehyde; 6-Bromo-2,4-difluoro-m-tolualdehyde; Benzaldehyde, 6-bromo-2,4-difluoro-3-methyl-; 1879026-17-1; 6-Br-2,4-F2-3-Me-Benzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-2,4-difluoro-3-methylbenzaldehyde is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our commitment to quality assurance supports compliance with the stringent requirements of pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.